In conclusion, LVCD, whether LBBB or L-IVCD, was strongly associated with increased mortality in patients with and at-risk for CVD.Ĭopyright © 2019 Elsevier Inc. After adjustment, LBBB and L-IVCD were similarly associated with increased all-cause (LBBB: 2.3, p = 0.001 L-IVCD: 4.0, p 120 ms) and CVD status. The prevalence of QRS prolongation was 5.6% (1,240): 760 right bundle branch block (3.4%), 313 LBBB (1.4%), and 161 IVCD (0.7%), 95 subclassified L-IVCD (0.4%). Integral viable cell concentration (IVCD), understood as the concentration of viable cells that were working during the time the cell culture lasted, was calculated as area under curve by. Study patients were 63 ± 9 years, 64% female, 75% Caucasian, 23% with established CVD. Of 24,081 patients randomized, 22,067 (92%) were included with follow-up 34 ± 13 months. The primary outcome was adjudicated all-cause and cardiovascular (CV) mortality. (See 'Left bundle branch block' and 'Right bundle branch block' and 'ECG tutorial. More complete discussions of left and right bundle branch block are presented elsewhere. This topic will review the basic aspects of this problem 1,2. IVCD was subclassified if left ventricular conduction delay (LVCD) was present (L-IVCD) or absent (O-IVCD). Nonspecific intraventricular conduction delay exists if the ECG displays a widened QRS appearance that is neither a left bundle branch block (LBBB) nor a right. Delayed intraventricular conduction is a common clinical abnormality detected on the electrocardiogram (ECG). QRS duration was classified narrow (≤100 ms) versus prolonged (>100 ms) with additional categorization into left (LBBB) or right (RBBB) bundle branch block or nonspecific intraventricular conduction delay (IVCD). Patients with centrally adjudicated, nonpaced baseline ECGs were included. A post-hoc analysis was performed of the randomized-control PRECISION trial. We aimed to compare clinical outcomes of narrow versus prolonged intraventricular conduction on ECG stratified by QRS morphology and cardiovascular disease (CVD) status. The prognosis associated with prolonged intraventricular conduction on electrocardiogram (ECG) remains uncertain.
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